2H-1,4-Benzoxazin-3(4H)-one, 8-[(1R)-1-hydroxy-2-[[2-(4-methoxyphenyl)-1,1-dimethylethyl]amino]ethyl]-6-(phenylmethoxy)- - Names and Identifiers
2H-1,4-Benzoxazin-3(4H)-one, 8-[(1R)-1-hydroxy-2-[[2-(4-methoxyphenyl)-1,1-dimethylethyl]amino]ethyl]-6-(phenylmethoxy)- - Physico-chemical Properties
Molecular Formula | C28H32N2O5
|
Molar Mass | 476.56408 |
Density | 1.205±0.06 g/cm3(Predicted) |
Boling Point | 700.4±60.0 °C(Predicted) |
pKa | 12.18±0.20(Predicted) |
Storage Condition | 2-8℃ |
2H-1,4-Benzoxazin-3(4H)-one, 8-[(1R)-1-hydroxy-2-[[2-(4-methoxyphenyl)-1,1-dimethylethyl]amino]ethyl]-6-(phenylmethoxy)- - Upstream Downstream Industry
2H-1,4-Benzoxazin-3(4H)-one, 8-[(1R)-1-hydroxy-2-[[2-(4-methoxyphenyl)-1,1-dimethylethyl]amino]ethyl]-6-(phenylmethoxy)- - Introduction
8-[(1R)-1-Hydroxy-2-[[2-(4-methoxyphenyl)-1,1-dimenthyyl] amino]ethyl]-6-(phenylmethoxy)-2H-1,4-benzoxazin-3(4H)-one is an organic compound whose structure is shown below:
Its chemical properties are as follows:
-Molecular formula: C31H38N2O4
-Molecular weight: 502.65g/mol
-Appearance: White or almost white crystalline powder
-Melting point: 137-140 ° C
-Solubility: Soluble in organic solvents such as dimethyl sulfoxide, dichloromethane, methanol and ethanol, insoluble in water.
Its main uses are:
-Catalyst: It can be used as a chiral catalyst to catalyze various chemical reactions in organic synthesis.
-Drug intermediates: can be used to synthesize drugs with biological activity.
The preparation method can be achieved through the following steps:
1. React 4-methoxybenzyl alcohol with dimethyl sulfoxide to generate 4-methoxybenzyl alcohol dimethyl sulfide.
2.4-Methoxybenzyl dimethyl sulfide reacts with N,N-dimethyl-N-(2-hydroxyethyl) formamide to generate the corresponding amination product.
3. The amination product reacts with benzyl bromide to generate the target compound.
Regarding safety information, due to lack of specific information, detailed information cannot be provided. Please refer to the relevant safety data sheet (SDS) or consult a professional before use. When using chemicals, it is recommended to observe proper laboratory procedures and safety measures, and to wear appropriate personal protective equipment.
Last Update:2024-04-09 15:18:03